Your Gut: The Hidden Key to Healthy Aging

A healthy gut supports digestion, immunity, mental clarity, and brain health as you age.

Your gut is home to trillions of microbes that influence how you feel, think, and function every day.

As we age, this system becomes more fragile. Supporting it consistently can help maintain regularity, reduce inflammation, and protect brain health over time.

Understanding Your Microbiome: A Guide for Healthy Aging

  • What is it

    Your microbiome is a vast community of trillions of microbes, including bacteria, viruses, and fungi, that live in your gut.

    Why it matters

    These microbes play a crucial role in your overall health, from supporting your immune system to helping digest food and even influencing your mood.

    A balanced microbiome is essential for maintaining good health as you age, as it helps protect against harmful pathogens, supports the production of vital nutrients and keeps your digestive tract working properly. [1][2].

    ✅ This balance is shaped every day by what you eat, how you move, and how you support your gut over time.

  • Healthy gut: Balanced microbes, strong gut lining, healthy production of short-chain fatty acids (SCFAs).

    Dysbiosis: Microbial imbalance that can disrupt digestion and increase inflammation.

    Leaky gut: A weakened gut lining that allows inflammatory signals to pass into the bloodstream.

Why Fiber Is More Than Just 'Roughage'

✅ The right fiber helps feed beneficial gut bacteria, reduce inflammation, and support regularity, all while supporting brain health.

Fiber is a type of carbohydrate your body can’t digest, but your gut bacteria can. When bacteria ferment fiber, they produce short-chain fatty acids (SCFAs), which help support a healthy gut lining and a balanced microbial environment.

This process does more than keep digestion moving. SCFAs play an important role in regulating inflammation and maintaining the gut barrier, which supports long-term gut and brain health.

The type and diversity of fiber you consume matters. [5][6]

How Your Gut Turns Fiber into Fuel for Your Brain & Body

✅ A diet rich in fiber supports the production of SCFAs, which act as a key link between what you eat and how your gut and brain function.

1. Fiber feeds gut bacteria
When gut bacteria break down fiber, they produce short-chain fatty acids (SCFAs).

2. SCFAs support the gut barrier
SCFAs help nourish the cells lining the colon, regulate inflammation, and maintain a healthy gut environment.

3. This supports whole-body health
Higher SCFA production has been linked with protective effects in the colon and supports overall gut–brain health. [3][4]

Your Gut and Brain Talk. Here's What They're Saying.

✅ A healthy, balanced microbiome helps regulate mood, stress, and thinking by supporting the gut–brain connection at its source.

Ever get “butterflies” in your stomach or feel nauseous when you’re stressed? That’s your gut–brain axis in action.

Your gut and brain are in constant, two-way communication through nerves, immune signals, and chemicals produced by your gut microbiome. This connection helps regulate digestion, stress response, mood, and cognitive function, often before you’re consciously aware of it.

Sometimes called the body’s “second brain,” the nervous system in your gut helps manage digestion and alerts the brain when something is out of balance. When this system is supported, communication stays calm and steady. When it’s disrupted, the brain can feel the effects.

Research shows the gut microbiome plays a meaningful role in this connection. Certain gut bacteria are involved in producing neurotransmitters such as serotonin, which influences emotional well-being, stress response, and mental clarity.

Supporting gut health is one of the ways this gut–brain conversation stays balanced over time.

Microbiome & Constipation

✅ By feeding your microbiome the right fiber, you may support gut motility, reduce straining, and feel more comfortable day to day.

Constipation isn’t just uncomfortable. It can be a sign that communication between your gut and brain is out of sync.

Constipation is often associated with an imbalance in the gut microbiome. When the diet lacks sufficient fiber, gut bacteria produce fewer short-chain fatty acids (SCFAs), which play an important role in supporting healthy bowel movements and gut motility.

Stress and anxiety can also influence digestion. Through the gut–brain axis, signals from the brain can slow gut movement, making constipation more likely during periods of chronic stress.

In neurological conditions, such as Parkinson’s disease, changes in dopamine signaling can further affect gut motility. This helps explain why constipation is a common and often early symptom in people with Parkinson’s.

Supporting a fiber-rich diet and a balanced microbiome is one way to help maintain healthy bowel function over time. [8]

How a Neurologist Uncovered the Gut-Brain Link in Parkinson’s

✅ In 2003, Braak’s hypothesis helped change how scientists think about the gut-brain connection.

In the early 2000s, German neurologist Heiko Braak proposed a hypothesis suggesting that Parkinson’s disease may begin in the gut before affecting the brain. Based on post-mortem studies, Braak observed patterns of pathology that appeared to move from the gastrointestinal tract to the brain along the vagus nerve.

This hypothesis drew attention to the role of gut inflammation, microbial imbalance, and reduced production of short-chain fatty acids in people with Parkinson’s. These changes may create an environment in the gut that contributes to disease progression, although research is ongoing.

Braak’s work helped spark decades of further study into the gut–brain axis and its potential role in neurological disease. While not all researchers agree on every aspect of the hypothesis, it has been highly influential in shaping how scientists investigate Parkinson’s today.

NeuroFiber was developed in response to this growing body of research, with the goal of supporting gut health through targeted, science-informed nutrition.

Not Just Theory, Real Results You Can See & Feel

Two studies were conducted evaluating daily NeuroFiber intake.

These results reflect outcomes observed in small human studies and are not intended to diagnose, treat, cure, or prevent disease.

  • Less Inflammation in 4-Weeks*

    Fecal calprotectin is a commonly used marker of gut inflammation. Average levels decreased after four weeks of daily NeuroFiber intake, suggesting a reduction in gut inflammation (p = 0.0206).

  • Improvements in Digestive Comfort*

    Participants reported improvements in constipation, bowel regularity, and stool consistency during the four-week trial.
    Many also reported reduced straining and less reliance on laxatives.

  • Improvements in Cholesterol Markers*

    Reductions in total cholesterol, LDL cholesterol, and non-HDL cholesterol were observed after four weeks of daily NeuroFiber intake.
    LDL is considered the 'bad' cholesterol. 

*Results based on 4-Week Pilot Clinical study (ncttrial.gov NCT07127120

What Participants Really Felt

Clinical measurements tell part of the story. Participants also reported noticeable changes in how they felt and functioned day to day during the four-week study.

  • Sleep & Energy

    Many participants reported improved sleep quality and feeling more rested, supporting better energy levels during the day.

  • Digestive Comfort

    Less straining. More predictable mornings. Many participants noticed meaningful digestive relief by the end of the study.

  • Daily Function

    Participants reported feeling more capable in daily life, including improvements in both physical and non-motor experiences.

How NeuroFiber Boosted Gut Health in Lab Models

To better understand how NeuroFiber may support the gut environment, researchers also evaluated its effects in a controlled lab model.

Because people with Parkinson’s disease are known to have reduced production of short-chain fatty acids (SCFAs), one of NeuroFiber’s goals is to help restore this critical microbial activity. SCFAs play an important role in maintaining a healthy gut lining and supporting balanced digestion.

Using Cryptobiotix’s ex-vivo SIFR® technology, researchers studied the impact of NeuroFiber prebiotic bars on key fermentation markers including pH, gas production, and SCFA levels in gut microbiota samples from people with Parkinson’s disease.

In this simulated gut environment, NeuroFiber stimulated higher total SCFA production than Miralax and Metamucil, two leading constipation remedies. SCFAs are a key metabolite to facilitate better gut health. The results also showed a meaningful decrease in pH, an important factor in discouraging the growth of pathogenic bacteria.

These findings help explain how NeuroFiber may support gut health by directly nourishing beneficial gut bacteria, offering a biological mechanism that aligns with the improvements observed in human studies.

An Individual Case Example

Illustrating longer-term use in one individual. Results may vary.

  • “I experienced a daily struggle with constipation. I'm eternally grateful for these bars, they have changed my life for the better.”

    Joel R

  • After completing the four-week clinical trial, one participant chose to continue using NeuroFiber daily.

    This individual example illustrates how gut inflammation levels changed over time with continued use beyond the formal study period.

    • Fecal calprotectin decreased from 259 µg/g to 15 µg/g
    • Levels shifted from elevated to within the normal range
    • Measurements collected over approximately five months

    Individual data shown with permission. Results may vary.

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